TS
| Investor | Type | Est. change | Change | Δ Own | Date | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Goldman Sachs Group Inc
· Added
Change
+8.7M
Date
Q1 2026
|
Goldman Sachs Group Inc | Added· Q1 2026 | – | +8.7M | – | Q1 2026 | |||||
|
Vestal Point Capital, LP
· Added
Change
+4.2M
Date
Q1 2026
|
Vestal Point Capital, LP | Added· Q1 2026 | – | +4.2M | – | Q1 2026 | |||||
|
Point72 Asset Management, L.P.
· Reduced
Change
−3.4M
Δ Own
−88.1%
Date
Q1 2026
|
Point72 Asset Management, L.P. | Reduced· Q1 2026 | – | −3.4M | −88.1% | Q1 2026 | |||||
|
Barclays PLC
· Reduced
Change
−2.7M
Date
Q1 2026
|
Barclays PLC | Reduced· Q1 2026 | – | −2.7M | – | Q1 2026 | |||||
|
Rtw Investments, LP
· Reduced
Change
−2.7M
Date
Q1 2026
|
Rtw Investments, LP | Reduced· Q1 2026 | – | −2.7M | – | Q1 2026 | |||||
|
Affinity Asset Advisors, LLC
· Reduced
Change
−2.3M
Date
Q1 2026
|
Affinity Asset Advisors, LLC | Reduced· Q1 2026 | – | −2.3M | – | Q1 2026 | |||||
|
Polar Capital Holdings PLC
· Reduced
Change
−2.3M
Date
Q1 2026
|
Polar Capital Holdings PLC | Reduced· Q1 2026 | – | −2.3M | – | Q1 2026 | |||||
|
Norges
· Exited
Change
−1.8M
Δ Own
−100.0%
Date
Q1 2026
|
Norges | Exited· Q1 2026 | – | −1.8M | −100.0% | Q1 2026 | |||||
|
Casdin Capital, LLC
· Added
Change
+1.8M
Date
Q1 2026
|
Casdin Capital, LLC | Added· Q1 2026 | – | +1.8M | – | Q1 2026 | |||||
|
Citadel Advisors LLC
· Reduced
Change
−1.4M
Δ Own
−77.8%
Date
Q1 2026
|
Citadel Advisors LLC | Reduced· Q1 2026 | – | −1.4M | −77.8% | Q1 2026 | |||||
|
SG Americas Securities, LLC
· Added
Change
+1.4M
Date
Q1 2026
|
SG Americas Securities, LLC | Added· Q1 2026 | – | +1.4M | – | Q1 2026 | |||||
|
Adage Capital Partners Gp, L.L.C.
· Exited
Change
−1.3M
Δ Own
−100.0%
Date
Q1 2026
|
Adage Capital Partners Gp, L.L.C. | Exited· Q1 2026 | – | −1.3M | −100.0% | Q1 2026 | |||||
|
Siren, L.L.C.
· Reduced
Change
−1.3M
Date
Q1 2026
|
Siren, L.L.C. | Reduced· Q1 2026 | – | −1.3M | – | Q1 2026 | |||||
|
Invesco Ltd.
· Reduced
Change
−965K
Δ Own
−72.4%
Date
Q1 2026
|
Invesco Ltd. | Reduced· Q1 2026 | – | −965K | −72.4% | Q1 2026 | |||||
|
Healthcare of Ontario Pension Plan Trust Fund
· Reduced
Change
−839K
Date
Q1 2026
|
Healthcare of Ontario Pension Plan Trust Fund | Reduced· Q1 2026 | – | −839K | – | Q1 2026 | |||||
| Insider | Title | Type | Price | Qty | Value | Owned | ΔOwn | Trade date | Filed date | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Nagendran Sukumar
· Director
Sell
−$1.2M
|
Nagendran Sukumar | Director | Sell | $6.24 | −200K | −$1.2M | 936K | −17.6% | Jul 10, 2026 | Jul 10, 2026 | |||||||||
|
Stalfort John A. III
· Director
2 operations
64K
|
Stalfort John A. III | Director | 2 operations | – | 64K | – | 43K | – | Jun 1, 2026 | Jun 2, 2026 | |||||||||
|
Donenberg Phillip B.
· Director
2 operations
64K
|
Donenberg Phillip B. | Director | 2 operations | – | 64K | – | 43K | – | Jun 1, 2026 | Jun 2, 2026 | |||||||||
|
Long Alison S.
· Director
2 operations
64K
|
Long Alison S. | Director | 2 operations | – | 64K | – | 43K | – | Jun 1, 2026 | Jun 2, 2026 | |||||||||
|
Sepp-Lorenzino Laura
· Director
2 operations
64K
|
Sepp-Lorenzino Laura | Director | 2 operations | – | 64K | – | 43K | – | Jun 1, 2026 | Jun 2, 2026 | |||||||||
|
Nagendran Sukumar
· Director
Sell
−$892K
|
Nagendran Sukumar | Director | Sell | $4.46 | −200K | −$892K | 1.1M | – | Apr 10, 2026 | Apr 13, 2026 | |||||||||
|
Nagendran Sukumar
· Director
2 operations
0
|
Nagendran Sukumar | Director | 2 operations | $1.71 | 0 | – | 456K | – | Apr 10, 2026 | Apr 13, 2026 | |||||||||
|
Alam Kamran
· Officer
Sell
−$7K
|
Alam Kamran | Officer | Sell | $4.52 | −2K | −$7K | 1.4M | – | Feb 4, 2026 | Feb 6, 2026 | |||||||||
|
Nagendran Sukumar
· Director, Officer
Sell
−$124K
|
Nagendran Sukumar | Director, Officer | Sell | $4.61 | −27K | −$124K | 1.3M | – | Jan 26, 2026 | Jan 27, 2026 | |||||||||
|
Nolan Sean P.
· Director
Sell
−$190K
|
Nolan Sean P. | Director | Sell | $4.61 | −41K | −$190K | 2.9M | – | Jan 26, 2026 | Jan 27, 2026 | |||||||||
|
Alam Kamran
· Officer
Sell
−$110K
|
Alam Kamran | Officer | Sell | $4.61 | −24K | −$110K | 1.4M | – | Jan 26, 2026 | Jan 27, 2026 | |||||||||
|
Nagendran Sukumar
· Director, Officer
Sell
−$423K
|
Nagendran Sukumar | Director, Officer | Sell | $4.75 | −89K | −$423K | 1.3M | – | Jan 23, 2026 | Jan 27, 2026 | |||||||||
|
Nolan Sean P.
· Director
Sell
−$650K
|
Nolan Sean P. | Director | Sell | $4.75 | −137K | −$650K | 2.9M | – | Jan 23, 2026 | Jan 27, 2026 | |||||||||
|
Alam Kamran
· Officer
Sell
−$375K
|
Alam Kamran | Officer | Sell | $4.75 | −79K | −$375K | 1.5M | – | Jan 23, 2026 | Jan 27, 2026 | |||||||||
|
Alam Kamran
· Officer
2 operations
590K
|
Alam Kamran | Officer | 2 operations | – | 590K | – | 231K | – | Jan 12, 2026 | Jan 14, 2026 | |||||||||
179 reporting institutions disclosed TSHA position changes in the Q1 2026 snapshot.
For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.
An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.
Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.
Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.
A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.