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Taysha Gene Therapies, Inc. (TSHA) institutional ownership

Market cap$688M SectorHealthcare
Funds holding · Q1 2026
179
reported TSHA position changes
Top owners · Q1 2026
No disclosed owners are available.
Institutional activity · Q1 2026
Activity unavailable N/A
95 buyers · 84 sellers

Taysha Gene Therapies, Inc. (TSHA) price and institutional activity

Dates

Q1 2026

$0 bought by 95 investors
Goldman Sachs Group IncVestal Point Capital, LP +93 more
$0 sold by 84 investors
Point72 Asset Management, L.P.Barclays PLC +82 more
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Bought Sold Totals per quarter; hover a bar for the names.

Taysha Gene Therapies, Inc. (TSHA) institutional activity · 179

Investor Type Est. change Change Δ Own Date
Goldman Sachs Group Inc · Added
Change +8.7M Date Q1 2026
Goldman Sachs Group Inc Added· Q1 2026 +8.7M Q1 2026
Vestal Point Capital, LP · Added
Change +4.2M Date Q1 2026
Vestal Point Capital, LP Added· Q1 2026 +4.2M Q1 2026
Point72 Asset Management, L.P. · Reduced
Change −3.4M Δ Own −88.1% Date Q1 2026
Point72 Asset Management, L.P. Reduced· Q1 2026 −3.4M −88.1% Q1 2026
Barclays PLC · Reduced
Change −2.7M Date Q1 2026
Barclays PLC Reduced· Q1 2026 −2.7M Q1 2026
Rtw Investments, LP · Reduced
Change −2.7M Date Q1 2026
Rtw Investments, LP Reduced· Q1 2026 −2.7M Q1 2026
Affinity Asset Advisors, LLC · Reduced
Change −2.3M Date Q1 2026
Affinity Asset Advisors, LLC Reduced· Q1 2026 −2.3M Q1 2026
Polar Capital Holdings PLC · Reduced
Change −2.3M Date Q1 2026
Polar Capital Holdings PLC Reduced· Q1 2026 −2.3M Q1 2026
Norges · Exited
Change −1.8M Δ Own −100.0% Date Q1 2026
Norges Exited· Q1 2026 −1.8M −100.0% Q1 2026
Casdin Capital, LLC · Added
Change +1.8M Date Q1 2026
Casdin Capital, LLC Added· Q1 2026 +1.8M Q1 2026
Citadel Advisors LLC Reduced· Q1 2026 −1.4M −77.8% Q1 2026
SG Americas Securities, LLC · Added
Change +1.4M Date Q1 2026
SG Americas Securities, LLC Added· Q1 2026 +1.4M Q1 2026
Adage Capital Partners Gp, L.L.C. · Exited
Change −1.3M Δ Own −100.0% Date Q1 2026
Adage Capital Partners Gp, L.L.C. Exited· Q1 2026 −1.3M −100.0% Q1 2026
Siren, L.L.C. · Reduced
Change −1.3M Date Q1 2026
Siren, L.L.C. Reduced· Q1 2026 −1.3M Q1 2026
Invesco Ltd. · Reduced
Change −965K Δ Own −72.4% Date Q1 2026
Invesco Ltd. Reduced· Q1 2026 −965K −72.4% Q1 2026
Healthcare of Ontario Pension Plan Trust Fund · Reduced
Change −839K Date Q1 2026
Healthcare of Ontario Pension Plan Trust Fund Reduced· Q1 2026 −839K Q1 2026
Data through Q1 2026 · filed Jun 4, 2026
15 of 179

Famous investor activity in Taysha Gene Therapies, Inc. (TSHA)

Taysha Gene Therapies, Inc. (TSHA) insider trading

Company insiders, action and economics first; trade and filed dates last.
Dates
Insider Title Type Price Qty Value Owned ΔOwn Trade date Filed date
Nagendran Sukumar · Director Sell −$1.2M
Price $6.24 Qty −200K Owned 936K ΔOwn −17.6% Trade date Jul 10, 2026 Filed date Jul 10, 2026
Nagendran Sukumar Director Sell $6.24 −200K −$1.2M 936K −17.6% Jul 10, 2026 Jul 10, 2026
Stalfort John A. III · Director 2 operations 64K
Owned 43K Trade date Jun 1, 2026 Filed date Jun 2, 2026
Stalfort John A. III Director 2 operations 64K 43K Jun 1, 2026 Jun 2, 2026
Donenberg Phillip B. · Director 2 operations 64K
Owned 43K Trade date Jun 1, 2026 Filed date Jun 2, 2026
Donenberg Phillip B. Director 2 operations 64K 43K Jun 1, 2026 Jun 2, 2026
Long Alison S. · Director 2 operations 64K
Owned 43K Trade date Jun 1, 2026 Filed date Jun 2, 2026
Long Alison S. Director 2 operations 64K 43K Jun 1, 2026 Jun 2, 2026
Sepp-Lorenzino Laura · Director 2 operations 64K
Owned 43K Trade date Jun 1, 2026 Filed date Jun 2, 2026
Sepp-Lorenzino Laura Director 2 operations 64K 43K Jun 1, 2026 Jun 2, 2026
Nagendran Sukumar · Director Sell −$892K
Price $4.46 Qty −200K Owned 1.1M Trade date Apr 10, 2026 Filed date Apr 13, 2026
Nagendran Sukumar Director Sell $4.46 −200K −$892K 1.1M Apr 10, 2026 Apr 13, 2026
Nagendran Sukumar · Director 2 operations 0
Price $1.71 Owned 456K Trade date Apr 10, 2026 Filed date Apr 13, 2026
Nagendran Sukumar Director 2 operations $1.71 0 456K Apr 10, 2026 Apr 13, 2026
Alam Kamran · Officer Sell −$7K
Price $4.52 Qty −2K Owned 1.4M Trade date Feb 4, 2026 Filed date Feb 6, 2026
Alam Kamran Officer Sell $4.52 −2K −$7K 1.4M Feb 4, 2026 Feb 6, 2026
Nagendran Sukumar · Director, Officer Sell −$124K
Price $4.61 Qty −27K Owned 1.3M Trade date Jan 26, 2026 Filed date Jan 27, 2026
Nagendran Sukumar Director, Officer Sell $4.61 −27K −$124K 1.3M Jan 26, 2026 Jan 27, 2026
Nolan Sean P. · Director Sell −$190K
Price $4.61 Qty −41K Owned 2.9M Trade date Jan 26, 2026 Filed date Jan 27, 2026
Nolan Sean P. Director Sell $4.61 −41K −$190K 2.9M Jan 26, 2026 Jan 27, 2026
Alam Kamran · Officer Sell −$110K
Price $4.61 Qty −24K Owned 1.4M Trade date Jan 26, 2026 Filed date Jan 27, 2026
Alam Kamran Officer Sell $4.61 −24K −$110K 1.4M Jan 26, 2026 Jan 27, 2026
Nagendran Sukumar · Director, Officer Sell −$423K
Price $4.75 Qty −89K Owned 1.3M Trade date Jan 23, 2026 Filed date Jan 27, 2026
Nagendran Sukumar Director, Officer Sell $4.75 −89K −$423K 1.3M Jan 23, 2026 Jan 27, 2026
Nolan Sean P. · Director Sell −$650K
Price $4.75 Qty −137K Owned 2.9M Trade date Jan 23, 2026 Filed date Jan 27, 2026
Nolan Sean P. Director Sell $4.75 −137K −$650K 2.9M Jan 23, 2026 Jan 27, 2026
Alam Kamran · Officer Sell −$375K
Price $4.75 Qty −79K Owned 1.5M Trade date Jan 23, 2026 Filed date Jan 27, 2026
Alam Kamran Officer Sell $4.75 −79K −$375K 1.5M Jan 23, 2026 Jan 27, 2026
Alam Kamran · Officer 2 operations 590K
Owned 231K Trade date Jan 12, 2026 Filed date Jan 14, 2026
Alam Kamran Officer 2 operations 590K 231K Jan 12, 2026 Jan 14, 2026
15 of 27
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Taysha Gene Therapies, Inc. (TSHA) activist and large shareholders

What are Schedules 13D and 13G?

Dates
Owner/Filer identity Shares reported % of shares outstanding Filing date
Ra Capital Management, L.P. 25.3M
% of shares outstanding 9.9% Filing date Aug 14, 2025
Ra Capital Management, L.P. 25.3M 9.9% Aug 14, 2025
Rtw Investments, LP 20.7M
% of shares outstanding 7.0% Filing date May 15, 2026
Rtw Investments, LP 20.7M 7.0% May 15, 2026
Blackrock, Inc. 13.5M
% of shares outstanding 6.6% Filing date Nov 8, 2024
Blackrock, Inc. 13.5M 6.6% Nov 8, 2024
Vestal Point Capital, LP 18.0M
% of shares outstanding 6.3% Filing date May 15, 2026
Vestal Point Capital, LP 18.0M 6.3% May 15, 2026
FMR LLC 15.6M
% of shares outstanding 6.2% Filing date Aug 6, 2025
FMR LLC 15.6M 6.2% Aug 6, 2025
Octagon Capital Advisors LP 10.4M
% of shares outstanding 5.1% Filing date Feb 5, 2025
Octagon Capital Advisors LP 10.4M 5.1% Feb 5, 2025
University of Texas/texas AM Investment Managment Co 1.2M
% of shares outstanding 3.0% Filing date Sep 24, 2021
University of Texas/texas AM Investment Managment Co 1.2M 3.0% Sep 24, 2021
BlackRock Inc. 1.0M
% of shares outstanding 2.6% Filing date Jul 8, 2022
BlackRock Inc. 1.0M 2.6% Jul 8, 2022
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Taysha Gene Therapies, Inc. (TSHA) ownership FAQ

Who owns TSHA?

179 reporting institutions disclosed TSHA position changes in the Q1 2026 snapshot.

How is institutional activity calculated?

For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.

What are activist and large shareholder filings?

An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.

Where does this data come from?

Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.

Why are ownership reports delayed?

Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.

How are missing table values shown?

A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.