Perceptive Advisors LLC
· Reduced
Change
−521K
Date
Q1 2026
| Investor | Type | Est. change | Change | Δ Own | Date | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Perceptive Advisors LLC
· Reduced
Change
−521K
Date
Q1 2026
|
Perceptive Advisors LLC | Reduced· Q1 2026 | – | −521K | – | Q1 2026 | |||||
|
Jennison Associates LLC
· Added
Change
+336K
Date
Q1 2026
|
Jennison Associates LLC | Added· Q1 2026 | – | +336K | – | Q1 2026 | |||||
|
Sio Capital Management, LLC
· New
Change
+294K
Date
Q1 2026
|
Sio Capital Management, LLC | New· Q1 2026 | – | +294K | – | Q1 2026 | |||||
|
Aberdeen Group PLC
· Reduced
Change
−276K
Date
Q1 2026
|
Aberdeen Group PLC | Reduced· Q1 2026 | – | −276K | – | Q1 2026 | |||||
|
Tpg Gp A, LLC
· Reduced
Change
−250K
Date
Q1 2026
|
Tpg Gp A, LLC | Reduced· Q1 2026 | – | −250K | – | Q1 2026 | |||||
|
Candriam S.c.a.
· New
Change
+237K
Date
Q1 2026
|
Candriam S.c.a. | New· Q1 2026 | – | +237K | – | Q1 2026 | |||||
|
JPMorgan Chase & Co
· Added
Change
+233K
Date
Q1 2026
|
JPMorgan Chase & Co | Added· Q1 2026 | – | +233K | – | Q1 2026 | |||||
|
Goldman Sachs Group Inc
· Added
Change
+227K
Date
Q1 2026
|
Goldman Sachs Group Inc | Added· Q1 2026 | – | +227K | – | Q1 2026 | |||||
|
Ensign Peak Advisors, Inc
· Added
Change
+176K
Date
Q1 2026
|
Ensign Peak Advisors, Inc | Added· Q1 2026 | – | +176K | – | Q1 2026 | |||||
|
Adage Capital Partners Gp, L.L.C.
· New
Change
+150K
Date
Q1 2026
|
Adage Capital Partners Gp, L.L.C. | New· Q1 2026 | – | +150K | – | Q1 2026 | |||||
|
Point72 Asset Management, L.P.
· New
Change
+137K
Date
Q1 2026
|
Point72 Asset Management, L.P. | New· Q1 2026 | – | +137K | – | Q1 2026 | |||||
|
Gordonmd Global Investments LP
· New
Change
+136K
Date
Q1 2026
|
Gordonmd Global Investments LP | New· Q1 2026 | – | +136K | – | Q1 2026 | |||||
|
Vanguard
· Added
Change
+110K
Date
Q1 2026
|
Vanguard | Added· Q1 2026 | – | +110K | – | Q1 2026 | |||||
|
Invesco Ltd.
· Reduced
Change
−100K
Δ Own
−90.3%
Date
Q1 2026
|
Invesco Ltd. | Reduced· Q1 2026 | – | −100K | −90.3% | Q1 2026 | |||||
|
Rhenman & Partners Asset Management AB
· New
Change
+88K
Date
Q1 2026
|
Rhenman & Partners Asset Management AB | New· Q1 2026 | – | +88K | – | Q1 2026 | |||||
| Insider | Title | Type | Price | Qty | Value | Owned | ΔOwn | Trade date | Filed date | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Thompson Peter A.
· Director
Sell
−$3.9M
|
Thompson Peter A. | Director | Sell | $44.86 | −86K | −$3.9M | 2.5M | −3.4% | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Orbimed Advisors LLC
· Director
Sell
−$3.9M
|
Orbimed Advisors LLC | Director | Sell | $44.86 | −86K | −$3.9M | 2.5M | −3.4% | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Fitzpatrick Jennifer
· Officer
Sell
−$447K
|
Fitzpatrick Jennifer | Officer | Sell | $43.60 | −10K | −$447K | 0 | −100.0% | Jul 6, 2026 | Jul 7, 2026 | |||||||||
|
Fitzpatrick Jennifer
· Officer
2 operations
0
|
Fitzpatrick Jennifer | Officer | 2 operations | $6.11 | 0 | – | 41K | – | Jul 6, 2026 | Jul 7, 2026 | |||||||||
|
Thompson Peter A.
· Director
Sell
−$5.3M
|
Thompson Peter A. | Director | Sell | $45.50 | −116K | −$5.3M | 2.6M | −4.3% | Jun 30, 2026 | Jul 2, 2026 | |||||||||
|
Orbimed Advisors LLC
· Director
Sell
−$5.3M
|
Orbimed Advisors LLC | Director | Sell | $45.50 | −116K | −$5.3M | 2.6M | −4.3% | Jun 30, 2026 | Jul 2, 2026 | |||||||||
|
Stelzer Laurie
· Director
Grant (A)
17K
|
Stelzer Laurie | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Viney Joanne L.
· Director
Grant (A)
17K
|
Viney Joanne L. | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Thompson Peter A.
· Director
Grant (A)
17K
|
Thompson Peter A. | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Ra Capital Management, L.P.
· Director
Grant (A)
17K
|
Ra Capital Management, L.P. | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Ruddy Marcella K.
· Director
Grant (A)
17K
|
Ruddy Marcella K. | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Resnick Joshua
· Director
Grant (A)
17K
|
Resnick Joshua | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Fleming Harold Edward
· Director
Grant (A)
17K
|
Fleming Harold Edward | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Clancy Paul J.
· Director
Grant (A)
17K
|
Clancy Paul J. | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Booth Bruce
· Director
Grant (A)
17K
|
Booth Bruce | Director | Grant (A) | – | 17K | – | 17K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
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107 reporting institutions disclosed SION position changes in the Q1 2026 snapshot.
For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.
An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.
Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.
Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.
A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.