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OPKO Health, Inc. (OPK) institutional ownership

Latest close $1.17 Jul 23, 2026
Market cap$1.0B 52-week range SectorHealthcare
Funds holding · Q1 2026
179
reported OPK position changes
Top owners · Q1 2026
No disclosed owners are available.
Institutional activity · Q1 2026
Activity unavailable N/A
94 buyers · 85 sellers

OPKO Health, Inc. (OPK) price and institutional activity

Dates

Q1 2026

$0 bought by 94 investors
Goldman Sachs Group IncBlackRock +92 more
$0 sold by 85 investors
AQR Capital Management LLCCitadel Advisors LLC +83 more
Bought Sold Totals per quarter; hover a bar for the names.

OPKO Health, Inc. (OPK) institutional activity · 179

Investor Type Est. change Change Δ Own Date
Goldman Sachs Group Inc · Added
Change +1.7M Date Q1 2026
Goldman Sachs Group Inc Added· Q1 2026 +1.7M Q1 2026
BlackRock · Added
Change +1.4M Date Q1 2026
BlackRock Added· Q1 2026 +1.4M Q1 2026
AQR Capital Management LLC · Reduced
Change −1.3M Date Q1 2026
AQR Capital Management LLC Reduced· Q1 2026 −1.3M Q1 2026
Op Asset Management Ltd · New
Change +1.1M Date Q1 2026
Op Asset Management Ltd New· Q1 2026 +1.1M Q1 2026
Citadel Advisors LLC Reduced· Q1 2026 −778K −27.2% Q1 2026
UBS Group AG · Added
Change +719K Date Q1 2026
UBS Group AG Added· Q1 2026 +719K Q1 2026
Jane Street Group, LLC · Reduced
Change −661K Date Q1 2026
Jane Street Group, LLC Reduced· Q1 2026 −661K Q1 2026
Hrt Financial LP · Reduced
Change −585K Date Q1 2026
Hrt Financial LP Reduced· Q1 2026 −585K Q1 2026
Two Sigma Investments, LP · Reduced
Change −565K Δ Own −76.9% Date Q1 2026
Two Sigma Investments, LP Reduced· Q1 2026 −565K −76.9% Q1 2026
State Street · Added
Change +550K Date Q1 2026
State Street Added· Q1 2026 +550K Q1 2026
Barclays PLC · Reduced
Change −525K Date Q1 2026
Barclays PLC Reduced· Q1 2026 −525K Q1 2026
Bank of America Corp · Added
Change +524K Date Q1 2026
Bank of America Corp Added· Q1 2026 +524K Q1 2026
First Trust Advisors LP · New
Change +500K Date Q1 2026
First Trust Advisors LP New· Q1 2026 +500K Q1 2026
Kovack Advisors, Inc. · New
Change +460K Date Q1 2026
Kovack Advisors, Inc. New· Q1 2026 +460K Q1 2026
Two Sigma Securities, LLC · Exited
Change −374K Δ Own −100.0% Date Q1 2026
Two Sigma Securities, LLC Exited· Q1 2026 −374K −100.0% Q1 2026
Data through Q1 2026 · filed Jun 8, 2026
15 of 179

Famous investor activity in OPKO Health, Inc. (OPK)

OPKO Health, Inc. (OPK) insider trading

Company insiders, action and economics first; trade and filed dates last.
Dates
Insider Title Type Price Qty Value Owned ΔOwn Trade date Filed date
Lachman Prem A. · Director Grant (A) 30K
Owned 30K Trade date Jun 18, 2026 Filed date Jun 22, 2026
Lachman Prem A. Director Grant (A) 30K 30K Jun 18, 2026 Jun 22, 2026
Medel Roger Md · Director Grant (A) 30K
Owned 30K Trade date Jun 18, 2026 Filed date Jun 22, 2026
Medel Roger Md Director Grant (A) 30K 30K Jun 18, 2026 Jun 22, 2026
Paganelli John A. · Director Grant (A) 30K
Owned 30K Trade date Jun 18, 2026 Filed date Jun 22, 2026
Paganelli John A. Director Grant (A) 30K 30K Jun 18, 2026 Jun 22, 2026
Pfenniger Richard C. Jr · Director Grant (A) 60K
Owned 60K Trade date Jun 18, 2026 Filed date Jun 22, 2026
Pfenniger Richard C. Jr Director Grant (A) 60K 60K Jun 18, 2026 Jun 22, 2026
Uppaluri Subbarao V · Director Grant (A) 80K
Owned 80K Trade date Jun 18, 2026 Filed date Jun 22, 2026
Uppaluri Subbarao V Director Grant (A) 80K 80K Jun 18, 2026 Jun 22, 2026
Yu Alice Lin-Tsing · Director Grant (A) 30K
Owned 30K Trade date Jun 18, 2026 Filed date Jun 22, 2026
Yu Alice Lin-Tsing Director Grant (A) 30K 30K Jun 18, 2026 Jun 22, 2026
Paganelli John A. · Director Buy +$11K
Price $1.14 Qty +10K Owned 394K Trade date Mar 20, 2026 Filed date Mar 20, 2026
Paganelli John A. Director Buy $1.14 +10K +$11K 394K Mar 20, 2026 Mar 20, 2026
Uppaluri Subbarao V · Director Grant (A) 50K
Owned 50K Trade date Mar 18, 2026 Filed date Mar 20, 2026
Uppaluri Subbarao V Director Grant (A) 50K 50K Mar 18, 2026 Mar 20, 2026
Frost Gamma Investments Trust · 10% Owner 5 operations +$770K
Price $1.30–$1.34 Qty +580K Owned 216.7M Trade date Nov 21, 2025 Filed date Nov 21, 2025
Frost Gamma Investments Trust 10% Owner 5 operations $1.30–$1.34 +580K +$770K 216.7M Nov 21, 2025 Nov 21, 2025
Frost Gamma Investments Trust · 10% Owner 7 operations +$772K
Price $1.32–$1.35 Qty +580K Owned 216.1M Trade date Nov 20, 2025 Filed date Nov 20, 2025
Frost Gamma Investments Trust 10% Owner 7 operations $1.32–$1.35 +580K +$772K 216.1M Nov 20, 2025 Nov 20, 2025
Frost Gamma Investments Trust · 10% Owner 9 operations +$761K
Price $1.28–$1.32 Qty +580K Owned 215.2M Trade date Nov 19, 2025 Filed date Nov 19, 2025
Frost Gamma Investments Trust 10% Owner 9 operations $1.28–$1.32 +580K +$761K 215.2M Nov 19, 2025 Nov 19, 2025
Frost Gamma Investments Trust · 10% Owner 11 operations +$681K
Price $1.25–$1.29 Qty +533K Owned 214.8M Trade date Nov 18, 2025 Filed date Nov 18, 2025
Frost Gamma Investments Trust 10% Owner 11 operations $1.25–$1.29 +533K +$681K 214.8M Nov 18, 2025 Nov 18, 2025
Frost Gamma Investments Trust · 10% Owner Grant (A) $59K
Price $1.26 Qty 47K Owned 214.5M Trade date Nov 18, 2025 Filed date Nov 18, 2025
Frost Gamma Investments Trust 10% Owner Grant (A) $1.26 47K $59K 214.5M Nov 18, 2025 Nov 18, 2025
Frost Phillip Md Et Al · Director, Officer, 10% Owner Buy +$213K
Price $1.42 Qty +150K Owned 214.4M Trade date Oct 31, 2025 Filed date Oct 31, 2025
Frost Phillip Md Et Al Director, Officer, 10% Owner Buy $1.42 +150K +$213K 214.4M Oct 31, 2025 Oct 31, 2025
Frost Phillip Md Et Al · Director, Officer, 10% Owner Gift (G) -440K
Owned 214.2M Trade date Aug 18, 2025 Filed date Aug 19, 2025
Frost Phillip Md Et Al Director, Officer, 10% Owner Gift (G) -440K 214.2M Aug 18, 2025 Aug 19, 2025
15 of 16
15 of 16 Sign in to continue to older insider transactions.

OPKO Health, Inc. (OPK) activist and large shareholders

Dates
Owner/Filer identity Shares reported % of shares outstanding Filing date
Rubric Capital Management LP 47.8M
% of shares outstanding 6.0% Filing date Jul 9, 2025
Rubric Capital Management LP 47.8M 6.0% Jul 9, 2025
Vanguard Group Inc 35.7M
% of shares outstanding 5.2% Filing date Feb 10, 2022
Vanguard Group Inc 35.7M 5.2% Feb 10, 2022
BlackRock Inc. 34.0M
% of shares outstanding 5.0% Filing date Mar 9, 2022
BlackRock Inc. 34.0M 5.0% Mar 9, 2022
3 of 3

OPKO Health, Inc. (OPK) ownership FAQ

Who owns OPK?

179 reporting institutions disclosed OPK position changes in the Q1 2026 snapshot.

How is institutional activity calculated?

For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.

What are activist and large shareholder filings?

An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.

Where does this data come from?

Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.

Why are ownership reports delayed?

Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.

How are missing table values shown?

A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.