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Orchestra BioMed Holdings, Inc. (OBIO) institutional ownership

Latest close $3.69 Jul 21, 2026
Market cap$161M 52-week range SectorHealthcare
Funds holding · Q1 2026
70
reported OBIO position changes
Top owners · Q1 2026
No disclosed owners are available.
Institutional activity · Q1 2026
Activity unavailable N/A
40 buyers · 30 sellers

Orchestra BioMed Holdings, Inc. (OBIO) price and institutional activity

Dates

Q1 2026

$0 bought by 40 investors
Propel Bio Management, LLCVanguard +38 more
$0 sold by 30 investors
T. Rowe Price AssociatesAffinity Asset Advisors, LLC +28 more
Bought Sold Totals per quarter; hover a bar for the names.

Orchestra BioMed Holdings, Inc. (OBIO) institutional activity · 70

Investor Type Est. change Change Δ Own Date
Propel Bio Management, LLC · New
Change +897K Date Q1 2026
Propel Bio Management, LLC New· Q1 2026 +897K Q1 2026
Vanguard · Added
Change +849K Date Q1 2026
Vanguard Added· Q1 2026 +849K Q1 2026
Millennium Management LLC · Added
Change +459K Date Q1 2026
Millennium Management LLC Added· Q1 2026 +459K Q1 2026
T. Rowe Price Associates · Exited
Change −365K Δ Own −100.0% Date Q1 2026
T. Rowe Price Associates Exited· Q1 2026 −365K −100.0% Q1 2026
Simplify Asset Management Inc. · New
Change +219K Date Q1 2026
Simplify Asset Management Inc. New· Q1 2026 +219K Q1 2026
Affinity Asset Advisors, LLC · Reduced
Change −170K Date Q1 2026
Affinity Asset Advisors, LLC Reduced· Q1 2026 −170K Q1 2026
Jane Street Group, LLC · Reduced
Change −118K Date Q1 2026
Jane Street Group, LLC Reduced· Q1 2026 −118K Q1 2026
Exoduspoint Capital Management, LP · Exited
Change −96K Δ Own −100.0% Date Q1 2026
Exoduspoint Capital Management, LP Exited· Q1 2026 −96K −100.0% Q1 2026
Perceptive Advisors LLC · Reduced
Change −89K Date Q1 2026
Perceptive Advisors LLC Reduced· Q1 2026 −89K Q1 2026
Renaissance Technologies LLC Reduced· Q1 2026 −80K −53.1% Q1 2026
Point72 Asset Management, L.P. · Reduced
Change −74K Δ Own −45.7% Date Q1 2026
Point72 Asset Management, L.P. Reduced· Q1 2026 −74K −45.7% Q1 2026
Susquehanna International Group, LLP · Reduced
Change −58K Date Q1 2026
Susquehanna International Group, LLP Reduced· Q1 2026 −58K Q1 2026
Omers Administration Corp · Reduced
Change −51K Date Q1 2026
Omers Administration Corp Reduced· Q1 2026 −51K Q1 2026
Xtx Topco Ltd · Exited
Change −50K Δ Own −100.0% Date Q1 2026
Xtx Topco Ltd Exited· Q1 2026 −50K −100.0% Q1 2026
Citadel Advisors LLC Added· Q1 2026 +49K +162.4% Q1 2026
Data through Q1 2026 · filed Jun 3, 2026
15 of 70

Famous investor activity in Orchestra BioMed Holdings, Inc. (OBIO)

Orchestra BioMed Holdings, Inc. (OBIO) insider trading

Company insiders, action and economics first; trade and filed dates last.
Dates
Insider Title Type Price Qty Value Owned ΔOwn Trade date Filed date
Sherman Darren · Director Sell −$64K
Price $4.27 Qty −15K Owned 1.2M ΔOwn −1.3% Trade date Jul 1, 2026 Filed date Jul 2, 2026
Sherman Darren Director Sell $4.27 −15K −$64K 1.2M −1.3% Jul 1, 2026 Jul 2, 2026
Fain Eric S. · Director Tax withholding or exercise payment (F) -4K
Owned 105K ΔOwn −3.9% Trade date Jun 24, 2026 Filed date Jun 25, 2026
Fain Eric S. Director Tax withholding or exercise payment (F) -4K 105K −3.9% Jun 24, 2026 Jun 25, 2026
Pacitti David · Director Tax withholding or exercise payment (F) -4K
Owned 59K ΔOwn −6.1% Trade date Jun 24, 2026 Filed date Jun 25, 2026
Pacitti David Director Tax withholding or exercise payment (F) -4K 59K −6.1% Jun 24, 2026 Jun 25, 2026
Cleary Chris · Director Tax withholding or exercise payment (F) -4K
Owned 33K ΔOwn −9.5% Trade date Jun 24, 2026 Filed date Jun 25, 2026
Cleary Chris Director Tax withholding or exercise payment (F) -4K 33K −9.5% Jun 24, 2026 Jun 25, 2026
Mack John Prosper · Director Tax withholding or exercise payment (F) -4K
Owned 71K ΔOwn −4.7% Trade date Jun 24, 2026 Filed date Jun 25, 2026
Mack John Prosper Director Tax withholding or exercise payment (F) -4K 71K −4.7% Jun 24, 2026 Jun 25, 2026
Fain Eric S. · Director 2 operations 39K
Owned 21K Trade date Jun 23, 2026 Filed date Jun 25, 2026
Fain Eric S. Director 2 operations 39K 21K Jun 23, 2026 Jun 25, 2026
Pacitti David · Director 2 operations 39K
Owned 21K Trade date Jun 23, 2026 Filed date Jun 25, 2026
Pacitti David Director 2 operations 39K 21K Jun 23, 2026 Jun 25, 2026
Cleary Chris · Director Grant (A) 43K
Owned 43K Trade date Jun 23, 2026 Filed date Jun 25, 2026
Cleary Chris Director Grant (A) 43K 43K Jun 23, 2026 Jun 25, 2026
Connealy Pamela Ann · Director 2 operations 39K
Owned 21K Trade date Jun 23, 2026 Filed date Jun 25, 2026
Connealy Pamela Ann Director 2 operations 39K 21K Jun 23, 2026 Jun 25, 2026
Aryeh Jason · Director Grant (A) 43K
Owned 43K Trade date Jun 23, 2026 Filed date Jun 25, 2026
Aryeh Jason Director Grant (A) 43K 43K Jun 23, 2026 Jun 25, 2026
Mack John Prosper · Director Grant (A) 35K
Owned 75K ΔOwn +86.0% Trade date Jun 23, 2026 Filed date Jun 25, 2026
Mack John Prosper Director Grant (A) 35K 75K +86.0% Jun 23, 2026 Jun 25, 2026
Taylor Andrew Lawrence · CFO Tax withholding or exercise payment (F) -$146K
Price $4.02 Qty -36K Owned 593K Trade date Jun 10, 2026 Filed date Jun 12, 2026
Taylor Andrew Lawrence CFO Tax withholding or exercise payment (F) $4.02 -36K -$146K 593K Jun 10, 2026 Jun 12, 2026
Hochman David P. · Director 2 operations -$26K
Price $4.02 Qty -7K Owned 436K Trade date Jun 10, 2026 Filed date Jun 12, 2026
Hochman David P. Director 2 operations $4.02 -7K -$26K 436K Jun 10, 2026 Jun 12, 2026
Hochman David P. · Director Buy +$19K
Price $3.83 Qty +5K Owned 1.1M Trade date Jun 1, 2026 Filed date Jun 2, 2026
Hochman David P. Director Buy $3.83 +5K +$19K 1.1M Jun 1, 2026 Jun 2, 2026
Sherman Darren · Director Sell −$58K
Price $3.87 Qty −15K Owned 1.2M Trade date Jun 1, 2026 Filed date Jun 2, 2026
Sherman Darren Director Sell $3.87 −15K −$58K 1.2M Jun 1, 2026 Jun 2, 2026
15 of 65
15 of 65 Sign in to continue to older insider transactions.

Orchestra BioMed Holdings, Inc. (OBIO) activist and large shareholders

Dates
Owner/Filer identity Shares reported % of shares outstanding Filing date
Rtw Investments, LP 7.7M
% of shares outstanding 21.5% Filing date Aug 7, 2024
Rtw Investments, LP 7.7M 21.5% Aug 7, 2024
Medtronic PLC 5.9M
% of shares outstanding 16.4% Filing date Feb 14, 2024
Medtronic PLC 5.9M 16.4% Feb 14, 2024
Perceptive Advisors LLC 4.6M
% of shares outstanding 12.8% Filing date Jul 17, 2024
Perceptive Advisors LLC 4.6M 12.8% Jul 17, 2024
T. Rowe Price Associates 686K
% of shares outstanding 6.1% Filing date Feb 14, 2023
T. Rowe Price Associates 686K 6.1% Feb 14, 2023
Ra Capital Management, L.P. 610K
% of shares outstanding 5.4% Filing date Feb 14, 2023
Ra Capital Management, L.P. 610K 5.4% Feb 14, 2023
Smith Geoffrey Wade 1.7M
% of shares outstanding 5.4% Filing date Feb 7, 2023
Smith Geoffrey Wade 1.7M 5.4% Feb 7, 2023
Blackrock, Inc. 1.9M
% of shares outstanding 5.1% Filing date Nov 8, 2024
Blackrock, Inc. 1.9M 5.1% Nov 8, 2024
Hsac 2 Holdings, LLC 1.7M
% of shares outstanding 4.8% Filing date Aug 7, 2024
Hsac 2 Holdings, LLC 1.7M 4.8% Aug 7, 2024
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Orchestra BioMed Holdings, Inc. (OBIO) ownership FAQ

Who owns OBIO?

70 reporting institutions disclosed OBIO position changes in the Q1 2026 snapshot.

How is institutional activity calculated?

For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.

What are activist and large shareholder filings?

An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.

Where does this data come from?

Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.

Why are ownership reports delayed?

Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.

How are missing table values shown?

A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.