Sarissa Capital Management LP
· Reduced
−$28M
Change
−6.7M
Date
Q1 2026
IR
| Investor | Type | Est. change | Change | Δ Own | Date | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Sarissa Capital Management LP
· Reduced
−$28M
Change
−6.7M
Date
Q1 2026
|
Sarissa Capital Management LP | Reduced· Q1 2026 | −$28M | −6.7M | – | Q1 2026 | |||||
|
Two Sigma Advisers, LP
· Exited
−$13M
Change
−3.1M
Δ Own
−100.0%
Date
Q1 2026
|
Two Sigma Advisers, LP | Exited· Q1 2026 | −$13M | −3.1M | −100.0% | Q1 2026 | |||||
|
State Street
· Added
+$12M
Change
+3.0M
Date
Q1 2026
|
State Street | Added· Q1 2026 | +$12M | +3.0M | – | Q1 2026 | |||||
|
Two Sigma Investments, LP
· Added
+$12M
Change
+3.0M
Δ Own
+105.0%
Date
Q1 2026
|
Two Sigma Investments, LP | Added· Q1 2026 | +$12M | +3.0M | +105.0% | Q1 2026 | |||||
|
Arrowstreet Capital, Limited Partnership
· Added
+$12M
Change
+3.0M
Date
Q1 2026
|
Arrowstreet Capital, Limited Partnership | Added· Q1 2026 | +$12M | +3.0M | – | Q1 2026 | |||||
|
Bank of America Corp
· Reduced
−$12M
Change
−2.8M
Date
Q1 2026
|
Bank of America Corp | Reduced· Q1 2026 | −$12M | −2.8M | – | Q1 2026 | |||||
|
AQR Capital Management LLC
· Added
+$12M
Change
+2.8M
Date
Q1 2026
|
AQR Capital Management LLC | Added· Q1 2026 | +$12M | +2.8M | – | Q1 2026 | |||||
|
Jane Street Group, LLC
· Reduced
−$9.0M
Change
−2.2M
Date
Q1 2026
|
Jane Street Group, LLC | Reduced· Q1 2026 | −$9.0M | −2.2M | – | Q1 2026 | |||||
|
Dimensional
· Added
+$7.2M
Change
+1.8M
Date
Q1 2026
|
Dimensional | Added· Q1 2026 | +$7.2M | +1.8M | – | Q1 2026 | |||||
|
Vanguard
· Reduced
−$6.6M
Change
−1.6M
Date
Q1 2026
|
Vanguard | Reduced· Q1 2026 | −$6.6M | −1.6M | – | Q1 2026 | |||||
|
Goldman Sachs Group Inc
· Added
+$5.8M
Change
+1.4M
Date
Q1 2026
|
Goldman Sachs Group Inc | Added· Q1 2026 | +$5.8M | +1.4M | – | Q1 2026 | |||||
|
Susquehanna International Group, LLP
· Added
+$4.2M
Change
+1.0M
Date
Q1 2026
|
Susquehanna International Group, LLP | Added· Q1 2026 | +$4.2M | +1.0M | – | Q1 2026 | |||||
|
Armistice Capital, LLC
· Reduced
−$4.1M
Change
−997K
Date
Q1 2026
|
Armistice Capital, LLC | Reduced· Q1 2026 | −$4.1M | −997K | – | Q1 2026 | |||||
|
Geode
· Added
+$3.8M
Change
+920K
Date
Q1 2026
|
Geode | Added· Q1 2026 | +$3.8M | +920K | – | Q1 2026 | |||||
|
Jacobs Levy Equity Management, Inc
· Added
+$3.6M
Change
+873K
Date
Q1 2026
|
Jacobs Levy Equity Management, Inc | Added· Q1 2026 | +$3.6M | +873K | – | Q1 2026 | |||||
| Insider | Title | Type | Price | Qty | Value | Owned | ΔOwn | Trade date | Filed date | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Silver Ronald
· Officer
Sell
−$578K
|
Silver Ronald | Officer | Sell | $4.52 | −128K | −$578K | 314K | −29.0% | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Shepard Jay
· Director
Grant (A)
63K
|
Shepard Jay | Director | Grant (A) | – | 63K | – | 235K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
Kessler Marla L.
· Director
Grant (A)
63K
|
Kessler Marla L. | Director | Grant (A) | – | 63K | – | 229K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
Currie Mark G.
· Director
Grant (A)
63K
|
Currie Mark G. | Director | Grant (A) | – | 63K | – | 677K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
Duane Jon R.
· Director
Grant (A)
63K
|
Duane Jon R. | Director | Grant (A) | – | 63K | – | 254K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
Denner Alexander J.
· Director
Grant (A)
63K
|
Denner Alexander J. | Director | Grant (A) | – | 63K | – | 324K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
McHugh Julie
· Director
Sell
−$80K
|
McHugh Julie | Director | Sell | $3.73 | −22K | −$80K | 251K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
McHugh Julie
· Director
Grant (A)
63K
|
McHugh Julie | Director | Grant (A) | – | 63K | – | 272K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
Moukheibir Catherine
· Director
Grant (A)
63K
|
Moukheibir Catherine | Director | Grant (A) | – | 63K | – | 181K | – | Jun 16, 2026 | Jun 17, 2026 | |||||||||
|
Denner Alexander J.
· Director
Grant (A)
4K
|
Denner Alexander J. | Director | Grant (A) | – | 4K | – | 260K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Silver Ronald
· Officer
Grant (A)
25K
|
Silver Ronald | Officer | Grant (A) | – | 25K | – | 442K | – | May 19, 2026 | May 21, 2026 | |||||||||
|
Denner Alexander J.
· Director
2 operations
−$21M
|
Denner Alexander J. | Director | 2 operations | $3.05–$3.31 | −6.7M | −$21M | 9.2M | – | Mar 17, 2026 | Mar 17, 2026 | |||||||||
|
Denner Alexander J.
· Director
Grant (A)
4K
|
Denner Alexander J. | Director | Grant (A) | – | 4K | – | 256K | – | Mar 13, 2026 | Mar 17, 2026 | |||||||||
|
John Minardo
· Officer
Grant (A)
137K
|
John Minardo | Officer | Grant (A) | – | 137K | – | 500K | – | Mar 10, 2026 | Mar 12, 2026 | |||||||||
|
Martini Gregory S.
· Officer
Grant (A)
137K
|
Martini Gregory S. | Officer | Grant (A) | – | 137K | – | 297K | – | Mar 10, 2026 | Mar 12, 2026 | |||||||||
N
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215 reporting institutions disclosed IRWD position changes in the Q1 2026 snapshot.
For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.
An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.
Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.
Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.
A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.