ES
| Investor | Type | Est. change | Change | Δ Own | Date | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Wasatch Advisors LP
· Added
Change
+6.3M
Date
Q1 2026
|
Wasatch Advisors LP | Added· Q1 2026 | – | +6.3M | – | Q1 2026 | |||||
|
Two Sigma Investments, LP
· Added
Change
+4.7M
Δ Own
+99.5%
Date
Q1 2026
|
Two Sigma Investments, LP | Added· Q1 2026 | – | +4.7M | +99.5% | Q1 2026 | |||||
|
Orbimed Advisors LLC
· Added
Change
+4.6M
Date
Q1 2026
|
Orbimed Advisors LLC | Added· Q1 2026 | – | +4.6M | – | Q1 2026 | |||||
|
UBS Group AG
· Added
Change
+4.0M
Date
Q1 2026
|
UBS Group AG | Added· Q1 2026 | – | +4.0M | – | Q1 2026 | |||||
|
Armistice Capital, LLC
· New
Change
+3.9M
Date
Q1 2026
|
Armistice Capital, LLC | New· Q1 2026 | – | +3.9M | – | Q1 2026 | |||||
|
Two Sigma Advisers, LP
· Exited
Change
−3.5M
Δ Own
−100.0%
Date
Q1 2026
|
Two Sigma Advisers, LP | Exited· Q1 2026 | – | −3.5M | −100.0% | Q1 2026 | |||||
|
Millennium Management LLC
· Reduced
Change
−3.3M
Date
Q1 2026
|
Millennium Management LLC | Reduced· Q1 2026 | – | −3.3M | – | Q1 2026 | |||||
|
Privium Fund Management B.V.
· New
Change
+3.3M
Date
Q1 2026
|
Privium Fund Management B.V. | New· Q1 2026 | – | +3.3M | – | Q1 2026 | |||||
|
Eversept Partners, LP
· Reduced
Change
−2.1M
Date
Q1 2026
|
Eversept Partners, LP | Reduced· Q1 2026 | – | −2.1M | – | Q1 2026 | |||||
|
Point72 Asset Management, L.P.
· New
Change
+1.7M
Date
Q1 2026
|
Point72 Asset Management, L.P. | New· Q1 2026 | – | +1.7M | – | Q1 2026 | |||||
|
Marshall Wace, LLP
· Added
Change
+1.6M
Date
Q1 2026
|
Marshall Wace, LLP | Added· Q1 2026 | – | +1.6M | – | Q1 2026 | |||||
|
Walleye Capital LLC
· Reduced
Change
−1.6M
Date
Q1 2026
|
Walleye Capital LLC | Reduced· Q1 2026 | – | −1.6M | – | Q1 2026 | |||||
|
State Street
· Added
Change
+1.1M
Date
Q1 2026
|
State Street | Added· Q1 2026 | – | +1.1M | – | Q1 2026 | |||||
|
Rhenman & Partners Asset Management AB
· New
Change
+985K
Date
Q1 2026
|
Rhenman & Partners Asset Management AB | New· Q1 2026 | – | +985K | – | Q1 2026 | |||||
|
Royce & Associates LP
· Reduced
Change
−975K
Date
Q1 2026
|
Royce & Associates LP | Reduced· Q1 2026 | – | −975K | – | Q1 2026 | |||||
| Insider | Title | Type | Price | Qty | Value | Owned | ΔOwn | Trade date | Filed date | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Hoffman Robert E.
· Director
3 operations
-132K
|
Hoffman Robert E. | Director | 3 operations | – | -132K | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Carroll J. Martin
· Director
4 operations
-275K
|
Carroll J. Martin | Director | 4 operations | – | -275K | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Shepard Jay
· Director
4 operations
-262K
|
Shepard Jay | Director | 4 operations | – | -262K | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Fischer Seth H. Z.
· Director
4 operations
-239K
|
Fischer Seth H. Z. | Director | 4 operations | – | -239K | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Thompson John Craig
· Director
2 operations
-120K
|
Thompson John Craig | Director | 2 operations | – | -120K | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Harlow John B. Jr
· Officer
Shares transferred outside the market (D), often for tax or as a gift, not a market sale
-425K
|
Harlow John B. Jr | Officer | Shares transferred outside the market (D), often for tax or as a gift, not a market sale | – | -425K | – | 0 | −100.0% | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Looker Benjamin
· Officer
4 operations
-1.3M
|
Looker Benjamin | Officer | 4 operations | – | -1.3M | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Halladay Benjamin
· Officer
4 operations
-1.3M
|
Halladay Benjamin | Officer | 4 operations | – | -1.3M | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Koenig Sheldon L.
· Director
4 operations
-4.2M
|
Koenig Sheldon L. | Director | 4 operations | – | -4.2M | – | 0 | – | Jul 13, 2026 | Jul 13, 2026 | |||||||||
|
Looker Benjamin
· Officer
Sell
−$37K
|
Looker Benjamin | Officer | Sell | $3.16 | −12K | −$37K | 668K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Koenig Sheldon L.
· Director
Sell
−$169K
|
Koenig Sheldon L. | Director | Sell | $3.15 | −54K | −$169K | 2.1M | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Halladay Benjamin
· CFO
Sell
−$34K
|
Halladay Benjamin | CFO | Sell | $3.15 | −11K | −$34K | 703K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Thompson John Craig
· Director
Grant (A)
80K
|
Thompson John Craig | Director | Grant (A) | – | 80K | – | 80K | – | May 28, 2026 | Jun 1, 2026 | |||||||||
|
Shepard Jay
· Director
Grant (A)
80K
|
Shepard Jay | Director | Grant (A) | – | 80K | – | 164K | – | May 28, 2026 | Jun 1, 2026 | |||||||||
|
Hoffman Robert E.
· Director
Grant (A)
80K
|
Hoffman Robert E. | Director | Grant (A) | – | 80K | – | 85K | – | May 28, 2026 | Jun 1, 2026 | |||||||||
187 reporting institutions disclosed ESPR position changes in the Q1 2026 snapshot.
For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.
An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.
Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.
Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.
A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.