Rtw Investments, LP
· Added
Change
+2.5M
Date
Q1 2026
CE
| Investor | Type | Est. change | Change | Δ Own | Date | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Rtw Investments, LP
· Added
Change
+2.5M
Date
Q1 2026
|
Rtw Investments, LP | Added· Q1 2026 | – | +2.5M | – | Q1 2026 | |||||
|
Nea Management Company, LLC
· Reduced
Change
−1.2M
Date
Q1 2026
|
Nea Management Company, LLC | Reduced· Q1 2026 | – | −1.2M | – | Q1 2026 | |||||
|
Toronto Dominion Bank
· New
Change
+883K
Date
Q1 2026
|
Toronto Dominion Bank | New· Q1 2026 | – | +883K | – | Q1 2026 | |||||
|
Soleus Capital Management, L.P.
· Reduced
Change
−524K
Date
Q1 2026
|
Soleus Capital Management, L.P. | Reduced· Q1 2026 | – | −524K | – | Q1 2026 | |||||
|
Holocene Advisors, LP
· Reduced
Change
−325K
Date
Q1 2026
|
Holocene Advisors, LP | Reduced· Q1 2026 | – | −325K | – | Q1 2026 | |||||
|
Sio Capital Management, LLC
· Reduced
Change
−283K
Date
Q1 2026
|
Sio Capital Management, LLC | Reduced· Q1 2026 | – | −283K | – | Q1 2026 | |||||
|
Point72 Asset Management, L.P.
· New
Change
+280K
Date
Q1 2026
|
Point72 Asset Management, L.P. | New· Q1 2026 | – | +280K | – | Q1 2026 | |||||
|
Avoro Capital Advisors LLC
· Added
Change
+264K
Date
Q1 2026
|
Avoro Capital Advisors LLC | Added· Q1 2026 | – | +264K | – | Q1 2026 | |||||
|
Bank of America Corp
· Reduced
Change
−263K
Date
Q1 2026
|
Bank of America Corp | Reduced· Q1 2026 | – | −263K | – | Q1 2026 | |||||
|
Lord, Abbett & Co. LLC
· Added
Change
+258K
Date
Q1 2026
|
Lord, Abbett & Co. LLC | Added· Q1 2026 | – | +258K | – | Q1 2026 | |||||
|
Candriam S.c.a.
· Reduced
Change
−246K
Date
Q1 2026
|
Candriam S.c.a. | Reduced· Q1 2026 | – | −246K | – | Q1 2026 | |||||
|
Public Sector Pension Investment Board
· Exited
Change
−226K
Δ Own
−100.0%
Date
Q1 2026
|
Public Sector Pension Investment Board | Exited· Q1 2026 | – | −226K | −100.0% | Q1 2026 | |||||
|
Healthcare of Ontario Pension Plan Trust Fund
· Exited
Change
−222K
Δ Own
−100.0%
Date
Q1 2026
|
Healthcare of Ontario Pension Plan Trust Fund | Exited· Q1 2026 | – | −222K | −100.0% | Q1 2026 | |||||
|
First Turn Management, LLC
· New
Change
+211K
Date
Q1 2026
|
First Turn Management, LLC | New· Q1 2026 | – | +211K | – | Q1 2026 | |||||
|
Qube Research & Technologies Ltd
· Reduced
Change
−175K
Date
Q1 2026
|
Qube Research & Technologies Ltd | Reduced· Q1 2026 | – | −175K | – | Q1 2026 | |||||
| Insider | Title | Type | Price | Qty | Value | Owned | ΔOwn | Trade date | Filed date | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Baker Bros. Advisors LP
· Other
2 operations
−$318M
|
Baker Bros. Advisors LP | Other | 2 operations | $102.50 | −3.1M | −$318M | 4.4M | – | Jul 14, 2026 | Jul 16, 2026 | |||||||||
|
Murphy Polly A.
· Director
2 operations
0
|
Murphy Polly A. | Director | 2 operations | – | 0 | – | 14K | – | Jun 10, 2026 | Jun 12, 2026 | |||||||||
|
Buller Richard E.
· Director
2 operations
0
|
Buller Richard E. | Director | 2 operations | – | 0 | – | 13K | – | Jun 10, 2026 | Jun 12, 2026 | |||||||||
|
Murphy Polly A.
· Director
Grant (A)
2K
|
Murphy Polly A. | Director | Grant (A) | – | 2K | – | 7K | – | Jun 5, 2026 | Jun 9, 2026 | |||||||||
|
Dalvey David
· Director
Grant (A)
2K
|
Dalvey David | Director | Grant (A) | – | 2K | – | 2K | – | Jun 5, 2026 | Jun 9, 2026 | |||||||||
|
Romp Charles R.
· Director
Grant (A)
2K
|
Romp Charles R. | Director | Grant (A) | – | 2K | – | 2K | – | Jun 5, 2026 | Jun 9, 2026 | |||||||||
|
Nigon Richard
· Director
Grant (A)
2K
|
Nigon Richard | Director | Grant (A) | – | 2K | – | 81K | – | Jun 5, 2026 | Jun 9, 2026 | |||||||||
|
Furcht Leo
· Director
Grant (A)
2K
|
Furcht Leo | Director | Grant (A) | – | 2K | – | 13K | – | Jun 5, 2026 | Jun 9, 2026 | |||||||||
|
Buller Richard E.
· Director
Grant (A)
2K
|
Buller Richard E. | Director | Grant (A) | – | 2K | – | 2K | – | Jun 5, 2026 | Jun 9, 2026 | |||||||||
|
Laing Lance G.
· Director
2 operations
0
|
Laing Lance G. | Director | 2 operations | $9.89 | 0 | – | 20K | – | Jun 2, 2026 | Jun 4, 2026 | |||||||||
|
Buller Richard E.
· Director
2 operations
0
|
Buller Richard E. | Director | 2 operations | – | 0 | – | 8K | – | May 19, 2026 | May 20, 2026 | |||||||||
|
Dalvey David
· Director
Sell
−$3.5M
|
Dalvey David | Director | Sell | $140.68 | −25K | −$3.5M | 65K | – | May 4, 2026 | May 6, 2026 | |||||||||
|
Buller Richard E.
· Director
6 operations
−$1.3M
|
Buller Richard E. | Director | 6 operations | $137.00–$143.24 | −9K | −$1.3M | 7K | – | May 4, 2026 | May 6, 2026 | |||||||||
|
Buller Richard E.
· Director
2 operations
0
|
Buller Richard E. | Director | 2 operations | $5.10 | 0 | – | 654 | – | May 4, 2026 | May 6, 2026 | |||||||||
|
Nigon Richard
· Director
Gift (G)
-10K
|
Nigon Richard | Director | Gift (G) | – | -10K | – | 79K | – | Apr 9, 2026 | Apr 13, 2026 | |||||||||
N
A
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269 reporting institutions disclosed CELC position changes in the Q1 2026 snapshot.
For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.
An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.
Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.
Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.
A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.